PhD thesis of Juliana de Oliveira Mota (2016-2019)

Public health risk-benefit assessment is a discipline which recently emerged thanks to the efforts of public health authorities (especially EFSA). It aims to quantify risks and benefits globally (considering altogether chemical, microbiological and nutritional aspects) and express them into a common metric (e.g. number of ill, number of lost or gained years of life) in order, in a second step, to give recommendations to producers, food processers and /or consumers to mitigate risks and increase benefits.
The objective of the PhD thesis is to apply new concepts to the beef meat model, by considering toxicological  (e.g. potential adverse health effects: colorectal cancer), microbiological (e.g.potential adverse health effects: foodborne outbreaks) and nutritional (e.g. potential beneficial health effect: coverage of protein requirements) aspects. This assessment will enable to converge towards a global health assessment associated with the preparation /consumption of red meat which, although possibly incomplete, will lay down the foundation. The developed methodology will also enable to identify the gaps and hence open other paths of research. At last, although methodological, the study will enable to identify and evaluate recommentations towards consumers regarding preparation, cooking and consumption of beef meat.
The PhD project called VacaRisk requires different scientific disciplines, including microbiology, chemistry, nutrition, applied statistics, mathematical modelling, probability calculations ; it falls within the thematical field of food safety and more generally in public health.

Keywords: Risk-Benefit assessment -  meat - Quantitative Microbiological Risk Assessment - Modeling - Food safety - Epidémiology - Nutrition

Valorisation:

• De Oliveira Mota, J., P. Tounian, S. Guillou, F. Pierre and J.-M. Membré 2019. Estimation of the burden of iron deficiency anemia in france from iron intake: Methodological approach. Nutrients 11(2045): 1-18. Ranking du JCR: Q1. https://doi.org/10.3390/nu11092045 
• De Oliveira Mota, J., G. Boué, S. Guillou, F. Pierre and J.-M. Membré 2019. Estimation of the burden of disease attributable to red meat consumption in France: Influence on colorectal cancer and cardiovascular diseases. Food and Chemical Toxicology 130: 174-186. Ranking du JCR: Q1. https://doi.org/10.1016/j.fct.2019.05.023.
• De Oliveira Mota, J., S. Guillou, F. Pierre and J.-M. Membré 2020. Quantitative assessment of microbiological risks due to red meat consumption in France. Microbial Risk Analysis: 100103. Ranking du JCR: Q2 (JCR® 2019). https://doi.org/10.1016/j.mran.2020.100103.
• De Oliveira Mota, J., S. Guillou, F. Pierre and J.-M. Membré 2021. Public health risk-benefit assessment of red meat in France: Current consumption and alternative scenarios. Food and Chemical Toxicology 149: 111994. https://doi.org/10.1016/j.fct.2021.111994